宸撮???????锛??冲??绌块???ョ?瑰?寤虹?????绌虹?妫?锛???椹冲?版??ㄦ繁????璧板?????绌烘?涓?讥婕???楂?绾у??堕?姘寸??娓??凤?涓?涓?绉???灞?璐ㄦ?????峰郴姘???氦缁??ㄤ?璧枫??????浜虹???????借???﹀?ㄩ?ｆ????????姗℃?ㄩ?ㄥ??锛???涓轰?澶╋?杩????冲?涓?婕?涓??衡??充??????粹??????寮????????板?帮?杩?涓???瀛??ㄤ??瑰?缇?????绯讳腑??涔?绛???浜???缁??测??浜?瀛?锛???濂圭??瀵规??锛??????涓???绉?涓?绉颁负??榛?????????绉??????姐??
??璋?????榛???????锛?骞娥???????瀹?瀛??ㄧ?????╋??????跺?涓?缇?瀹圭???棰?????涓?涓?护浜虹??????绗﹀?枫??瀹?????伴????浜?娣辨捣榛????宠?介??涓?楂?绮惧????叉??????宸?宄颁华?????浣?婕?榛?锛?绾挎?″?峰郴濡???濉?锛??ｅ????涓?绉???浜哄?胯???宸ヤ?濞???????瀹?浠ｈ〃??涓?绉?缁?瀵圭??????锛?涓?绉??藉?褰火??″???濉?缁????昏?????????????????榛???绉?????
?ㄦ????涔???锛????板?璇?椹鹃┉瀹????㈠??藉?ㄥ?剁???寸???介?????句??惧???涓?浠?蹇?锛????冲?ㄩ?ｈ?＄函绮桂??????烘??????㈠???惧????姐??
褰????板?版?ㄩ?ㄨ???ユ?讹?绌烘?浼间????村???恒??濂规病??绌块?ｇ????锋?诲?绘?х??绾㈡?绀兼??锛?????浠ｄ??????浠惰川?版???舵??杞?????涓??借‖琛???垮???炬?ｅ?板????″?ㄨ?╁ご锛????ゅ?ㄦ??????瀹ゅ????????涓?绉?杩?涔????????规鼎????杩?绉???搴︾????锛?涓???榛????????ｆ??搴︾??纭???ㄧ┖?撮??褰㈡??浜?涓?绉?寮?????瓒崇??瀵规???
??灏辨?????锛???濂硅交澹板??ｏ?澹伴?充?澶э??存????涓?瀹圭疆????纾??恒??
?㈠?杩??拌薄寰???纭??哥???????榛???????锛????板?板苟娌℃??琛ㄧ?板?烘????浜洪?ｆ?风??杩?????濂硅蛋杩?瀹?锛?????杞昏交婊?杩?瀹??板?风??榛??茬（??澶?澹炽???ｄ??伙?浠夸???袱?″????????娆¤????涓??规??俯濠?濡?姘寸??涓??归?靛?筹?涓??规??????濡??风??瑗挎?圭?????杩?绉?瀵瑰?锛?涓???负浜?娑?????癸?????负浜?瀵绘?句?绉?骞宠 锛?涓?绉??借?缇?瀛﹁法瓒??堕?撮缚娌??????姐??
?ㄥ?寸??涓?瀹跺?㈤??灞???互寰???ャ??浠?浠?繁?ワ?杩?娆♀??澶ф????骞堕????绾?????ヤ唬瑷???灞?绀猴??????娆＄??姝ｆ??涔?涓?????韬???烘???纾ㄥ???????板?伴??瑕??ㄨ??颁华?ㄧ????ユ??绔??介??涓?锛?缁存??浣?濂归?ｆ??蹇??х????ョ???锛????宠?????????锛??╃?ㄢ??榛????????????磋?介??婵?????韩?存繁灞?娆○???????藉????
??榛???????寮?濮??????浣?娌???楦ｅ??濡???娣辨捣宸ㄥ?界???煎?搞??瀹ゅ??????绾块????浠??ㄧ??杩?杞???????浜ゆ?匡???褰辨???ㄨ???板?扮???镐?锛??惧???吼??″ス瀹?缇???杞????濂归????硷?杩??ラ?ｄ??¤冻浠ユ??瑁?骞冲焊???介????杩?涓????娆℃俯????SPA锛???????烘?绀笺???ㄩ?ｄ??伙????板?拌〃?板?虹??涓?????ㄦ?ュ??锛??????绉?涓诲?ㄧ??杩??汇??
濂圭??姣?涓?涓??寰?〃???藉?ㄤ?杈句?绉?淇℃?????璁鸿?????澶?涔?寮烘í锛?濂归?借?藉??跺??涓哄繁?ㄣ??杩?绉?瀵圭??????ф?锛?杩?绉?楠ㄥ???????俊锛?姝ｆ??ス?藉?甯稿勾灞圭?浜?宸?宄扮??绉?瀵????ㄣ??
?ㄨ?涓???????寮?涓????浠????扮??涓?浠????涓?????????ヨ??涓?绱??伙??存???涓?コ?у?????杈圭?????㈢储??濂规繁?ワ???姝ｇ????ョ?浠??ヤ???俯瀹ら?????辨?碉??????ㄩ??翠腑蹇?渚??惰?戒???璧疯??????姘???
??????榛????????介??绛?绾х??????锛?瀹?楠?瀹ゅ????姘?姘?绱х环?颁????广??绌烘?涓??佃?锋?????ｇ??遍?棰??????插甫?ョ????杩???璁╁?ㄥ?虹????瑙????芥???拌?稿?ｅ???枫????澶?浜?椋??翠腑蹇??????板?帮??村??板?轰?涓?绉?浠や汉蹇?????????骞抽????
濡???璇寸?涓??舵????????ｄ??板???灏辨????姝ｇ????璐磋韩??????????榛??????????㈠ご?ㄥス?????や???杩?锛?姣?涓?娆″?????戒即????瓒充互绌块????????介????棰ゃ??杩?绉???瑙?琚?????????杩颁负???颁?????浜ゅ????锛????惰??楠???璇???????????涓???蹇????????板?扮??棰?澶存??虹?寰???姹???锛?浣??ㄧ??瑙??ㄧ??楂?娓???澶翠?锛?濂圭???肩?濮?缁?娣遍??????瀹???
濂逛豢浣??ㄨ?琛?涓??烘繁搴︾????瑙?锛???杩???浣???寰?????锛??昏Е?搁?ｄ釜琚??缇???瑁?涔???????ョ??瀹???????
杩?绉???澶ф????锛???川涓???汉绫诲?琛拌????瀵硅???舵??蹇???涓?娆″???????????板?帮?姝ｆ????哄????????????濂逛?浠?浠????ㄤ娇?ㄤ??颁华???濂规???ㄤ???榛???????杩?琛?涓??虹?甸?灞??㈢??瀵硅???濂圭?ㄨ??繁??姘??哄?绘???浠??ㄧ???板?凤??ㄨ??繁?????у?诲??瑁规?????????┿???㈡?㈠?帮???????韬????介??浼间???寰?椤烘??璧锋?ワ??ｄ?娌???杞伴福澹颁?涓????惧??鸿?筹??????????绉??よ????璇?????璇碉??ㄤ负杩?浣?濂崇????????
杩?绋???缁??杩?涓や釜灏??躲??褰?????涓??????插???????褰???榛??????????板??褰?姝诲???榛??诧??ㄥ?洪甫????澹般?????板?扮?缂???寮??硷??ｄ????达?濂圭???肩?涓?豢浣??磋???????撮?澶??????点??
?╃????涓??伴?????挎?姘达?濂规?ㄥ?浜???濂圭?璧疯韩锛?璧板???ｉ?㈠法澶х??绌胯。??????瀛?????濂癸????板?轰?绉????????????舵??锛?????簿?寸??浜?瀹??ㄨ?介????娲?绀间??惧??村??绔?浣?锛????や???浠?浠????界??锛?????????涓?绉?浠?缁???娣卞?娉靛?虹?????界孩娑︽??锛???????浠?娌??′腑???????借??锛???婊′????垮?????寮?????
杩?灏辨????衡??澶ф??????缁?????濂规病??琚???榛???????????ュ?????????????????杩?杩?绉????寸??瀵规??锛????や?韬?????叉???娌?????杩?涓?????浠????よ?ゅ??㈢?????╋??存???绉?蹇???灞??㈢????濉???濂圭?ㄨ??ㄨ???浜?锛???姝ｇ??寮鸿??浠?涓????у己澶х??宸ュ?凤??????ｅ伐?风??璧锋?ュ?烽?枫??榛??????锋???诲?绘?с??
??绉??????楠硷?瀹＄????甸?????濂瑰?ㄩ????????璁夸腑娣℃贰????拌?????搞??杩??ヨ?绮惧???版????杩??哄??崇?????搞???ㄢ??榛????????㈠??锛?濂规病?????╁Ε???????匡????????╂??涓鸿??″??????涓讳汉??
杩??衡?????板?板ぇ??榛???????????浜?锛?杩????ㄥ????浼?寮?锛???涓轰?涓??充???缇?涓??????????颁?璇淬??瀹???璇?姣?涓?涓?拷姹?缇???浜猴??ㄨ?涓????????哥???朵唬锛?涓?瑕?瀹虫???ｄ???璧锋?ヨ?浜?寮烘????涓?瑗裤????璁烘????娲荤??????锛?杩????堕?寸??娴???锛?浜︽?????ｄ??板?风??纭??哥???锛????浣??ユ??瓒冲?寮哄ぇ?????革?瀹?浠??灏???涓轰?????涓??????ㄧ???跺??┿??
???板?版???澶?濂?锛??ㄩ?ㄨ???猴?澶??㈢???冲??渚??х?跨??锛?浣?姝ゅ?荤??濂癸?宸茬?甯︿?浜???绉???榛???????璧?浜???????涓????х??璐ㄦ????濂逛??ф???ｄ釜缁??茬??濂崇??锛??????ㄨ?娆″ぇ??涔???锛?濂圭?????查??澶?浜?涓?浠芥?ヨ????澶???娣遍????????杩??鸿???娌℃??杈?瀹讹?????涓?娆″?充????翠?缇?????绾т?璺ㄨ???
uat 杈炬???ㄧ?????璁稿????ㄨ? KRAS G12D ???跺??锛?浜ゆ???婚???楂? 13 浜跨??? + ??绾х??绋?
????涓?杞?/a>
涓???缃?寰?俊